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A 68-year-old man was admitted to the hospital because of headache and loss of vision in the right eye. Orthotopic allogeneic liver transplantation had been performed 3 1/2 months earlier because of liver failure due to hepatitis C virus (HCV) infection. Perioperative medications included rabbit antithymocyte globulin, vancomycin, fluconazole, and piperacillin–tazobactam. Tacrolimus, azathioprine, furosemide, spironolactone, and a short course of corticosteroids were administered postoperatively. The immediate postoperative course was complicated by coagulopathy, intraperitoneal thrombi, and worsening renal function, with ascites and peripheral edema. The patient was discharged 2 weeks after transplantation.
He had persistent anorexia and fatigue, but his condition
Differential Diagnosis
Giant-Cell Arteritis
Anterior Ischemic Optic Neuropathy
Infections after Liver Transplantation
Dr. Margaret Seton's Diagnosis
Pathological Discussion
Anatomical Diagnoses
Source Information
From the Rheumatology, Allergy, and Immunology Division and Rheumatology Unit (M.S.), the Departments of Neurology (M.P.), Infectious Disease (J.A.F.), and Radiology (P.A.C.), and the Neuropathology Division, Department of Pathology (E.T.H.-W.), Massachusetts General Hospital; the Departments of Medicine (M.S., J.A.F.), Neurology (M.P.), Pathology (E.T.H.-W.), and Radiology (P.A.C.), Harvard Medical School; and the Department of Radiology, Massachusetts Eye and Ear Infirmary (P.A.C.).
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