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Previous Volume 361:1768-1775 October 29, 2009 Number 18 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the authors' clinical recommendations.

A 24-year-old man presents to an outpatient clinic, reporting that 36 hours previously he had receptive anal intercourse without the use of a condom with an anonymous male partner who was known to have had sex with other men. The patient is known to the clinical practice and has had several negative tests for human immunodeficiency virus (HIV) infection, most recently 6 . . . [Full Text of this Article]

The Clinical Problem

Strategies and Evidence

Assessing the Need for Postexposure Prophylaxis

Type of Exposure

            Occupational Exposure

            Nonoccupational Exposure

Characteristics of the Source Patient

Timing and Duration of Treatment

Regimens for Postexposure Prophylaxis

Baseline and Follow-up Assessments

            Testing of the Source Patient

            Baseline Testing of the Exposed Patient

Risks Associated with Postexposure Prophylaxis

Areas of Uncertainty

Guidelines

Conclusions and Recommendations

Source Information

From the University of California at Los Angeles (UCLA) Center for Clinical AIDS Research and Education and the David Geffen School of Medicine at UCLA, Los Angeles.

Address reprint requests to Dr. Landovitz at the UCLA Center for Clinical AIDS Research and Education, David Geffen School of Medicine, 9911 W. Pico Blvd., Suite 980, Los Angeles, CA 90035, or at rlandovitz@mednet.ucla.edu.

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