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Previous Volume 361:1776-1785 October 29, 2009 Number 18 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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The Norwalk agent was the first virus that was identified as causing gastroenteritis in humans, but recognition of its importance as a pathogen has been limited because of the lack of available, sensitive, and routine diagnostic methods. Recent advances in understanding the molecular biology of the noroviruses, coupled with applications of novel diagnostic techniques, have radically altered our appreciation of their impact. Noroviruses are now recognized as being the leading cause of epidemics of gastroenteritis and an important cause of sporadic gastroenteritis in both children and adults. Although norovirus gastroenteritis is generally mild and of short duration, new evidence suggests . . . [Full Text of this Article]

Characteristics and Evolution of Norovirus

Laboratory Diagnosis

Epidemiology and Transmission

Clinical Features

Pathogenesis

Host Susceptibility

Immunity

Prevention and Control

Vaccines

Treatment

Source Information

From the Fogarty International Center, National Institutes of Health, Bethesda, MD (R.I.G.); the Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta (R.I.G., U.D.P.); and Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston (M.K.E.).

Address reprint requests to Dr. Glass at Fogarty International Center, 31 Center Dr., Rm. 31 B2 C02, Bethesda, MD 20892.

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