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Editorial
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Volume 361:1804-1806 October 29, 2009 Number 18
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Antimicrobial Prophylaxis for Urinary Tract Infection in Children
Alejandro Hoberman, M.D., and Ron Keren, M.D., M.P.H.

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 by Craig, J. C.
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Approximately one third of children who have a urinary tract infection — the most frequent serious bacterial infection in young febrile children — have vesicoureteral reflux, a congenital condition in which the urine flow is retrograde from the bladder toward the kidneys during micturition. Data from observational studies and animal models support the hypothesis that children with vesicoureteral reflux who have urinary tract infection are at increased risk for renal scarring.

Vesicoureteral reflux is graded from I (lowest grade, with reflux into the ureter only) to V (highest grade, with marked ureteral tortuosity, calyceal blunting, and severely dilated renal pelvis). . . . [Full Text of this Article]


Source Information

From the Department of Pediatrics, Children's Hospital of Pittsburgh, Pittsburgh (A.H.); and the Department of Pediatrics and Center for Pediatric Clinical Effectiveness, Children's Hospital of Philadelphia, Philadelphia (R.K.).


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