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A 39-year-old woman with a 1-year history of Stage IV melanoma presented with progressive shortness of breath, fatigue, and edema in the legs, which had developed over the course of the previous week. At the time of the melanoma diagnosis, a mediastinal and right supraclavicular mass had been seen without identification of a primary tumor. The patient had been treated with five cycles of biochemotherapy and then with antibodies against cytotoxic T lymphocyte antigen 4. Subsequently, the superior vena cava syndrome and tracheal compression had developed, which had required stenting. The patient had then received radiation therapy. Integrated positron-emission tomography . . . [Full Text of this Article] |
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