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Previous Volume 346:1588-1589 May 16, 2002 Number 20 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: There is strong experimental and epidemiologic evidence that the use of acetaminophen or aspirin is associated with a very small risk of analgesic nephropathy. However, only extensive and uncontrolled consumption has been proved to be dangerous. Because there is a higher risk of acute renal impairment associated with cyclooxygenase inhibition, current practice is to ban the use of nonsteroidal antiinflammatory drugs (including high-dose aspirin) in patients with chronic renal failure and to recommend instead acetaminophen or low-dose aspirin.

The case–control study by Fored et al. (Dec. 20 issue)¹ apparently contradicts this view, but the data raise the . . . [Full Text of this Article]

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