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Review Article
Medical Progress
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Volume 355:928-939 August 31, 2006 Number 9
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Cerebral Aneurysms
Jonathan L. Brisman, M.D., Joon K. Song, M.D., and David W. Newell, M.D.

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Saccular intracranial aneurysms, abnormal focal outpouchings of cerebral arteries, cause substantial rates of morbidity and mortality. Recently, major changes have occurred in the way we think about and treat this disease. Previous concepts about the natural history, particularly the risk of rupture of certain aneurysms, have been challenged.1,2

When this topic was the subject of a Medical Progress article in the Journal in 1997, minimally invasive percutaneous endovascular treatment of intracranial aneurysms (a technique known as coiling) had been introduced as an experimental procedure for patients who were not good candidates for surgery.3 After almost a decade of increased use . . . [Full Text of this Article]

Epidemiology and Pathophysiology

Natural History and Risk of Rupture

Medical Diagnosis and Management of Subarachnoid Hemorrhage

Clinical Presentation and Diagnosis

Imaging Methods and Options

Clinical Approach to Imaging

Acute Effects of Subarachnoid Hemorrhage

Medical Therapy

Treatment Options

Comparison of Clipping and Coiling

            Risks of Clipping

            Risks of Inserting Detachable Coils

            Relative Risks of Coiling and Clipping

The Effects of Surgeon and Hospital Volume

Optimal Treatment of Aneurysms


Source Information

From the Department of Cerebrovascular and Endovascular Neurosurgery, New Jersey Neuroscience Institute, JFK Medical Center, Edison, N.J. (J.L.B.); the Department of Endovascular Surgery, Institute for Neurology and Neurosurgery, Roosevelt Medical Center, New York (J.K.S.); and the Department of Neurosurgery, Seattle Neuroscience Institute, Swedish Medical Center, Seattle (D.W.N.).

Address reprint requests to Dr. Brisman at the Department of Cerebrovascular and Endovascular Neurosurgery, New Jersey Neuroscience Institute at JFK Medical Center, Edison, NJ 08818, or at jbrisman@solarishs.org.


Related Letters:

Cerebral Aneurysms
Finucane F. M., Torres V. E., Pirson Y., Wiebers D. O., Whiteley W., Salman R. A.-S., Brisman J. L., Song J. K., Newell D. W.
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N Engl J Med 2006; 355:2703-2705, Dec 21, 2006. Correspondence

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