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Previous Volume 357:2153-2165 November 22, 2007 Number 21 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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The modern history of sarcoidosis, an enigmatic multisystem disease, goes back to 1899, when the pioneering Norwegian dermatologist Caesar Boeck coined the term to describe skin nodules characterized by compact, sharply defined foci of "epithelioid cells with large pale nuclei and also a few giant cells."¹ Thinking this resembled sarcoma, he called the condition "multiple benign sarcoid of the skin."¹

Since sarcoidosis was last reviewed in the Journal 10 years ago,² more than 5000 articles related to this condition have been published. This review summarizes recent advances and addresses pitfalls in the diagnosis and treatment of sarcoidosis.

Epidemiology

Sarcoidosis affects people . . . [Full Text of this Article]

Search for Environmental Causes

Genetic Features

Immunopathogenesis

Clinical Features

Diagnosis

Organ Involvement

Pulmonary Involvement

Cutaneous Involvement

Liver and Spleen Involvement

Neurologic Involvement

Ophthalmologic Complications

Cardiac Sarcoidosis

Hypercalcemia and Renal Disease

Bone and Joint Involvement

Sarcoidosis in Children

Therapy

Medications

Transplantation

Future Directions

Source Information

From the Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, Mount Sinai School of Medicine, New York (M.C.I., A.S.T.); and the Department of Biostatistics and Research Epidemiology, Henry Ford Health System, Detroit (B.A.R.).

Address reprint requests to Dr. Iannuzzi at the Division of Pulmonary, Critical Care, and Sleep Medicine, Mount Sinai Medical Center, 1 Gustave Levy Pl., Box 1232, New York, NY 10029, or at michael.iannuzzi@mssm.edu.

Related Letters:

Sarcoidosis
Murray J. A., Lyons J. L., Sharma S. K., Kadhiravan T., Guzzi G., Severi G., Catherinot E., Rivaud E., Couderc L.-J., O'Regan A. W., Fleming C. A., Fernández-Fernández F. J., Sesma P., Rodríguez-Rivas C., Bergot E., Paparel P., Zalcman G., Iannuzzi M. C., Teirstein A. S.
Extract | Full Text | PDF  
N Engl J Med 2008; 358:1402-1405, Mar 27, 2008. Correspondence

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