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FOCUS ON RESEARCH Previous Volume 358:2664-2665 June 19, 2008 Number 25 Next

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In 1987, an editorial accompanying a report on the use of high-dose interleukin-2 therapy for cancer asked whether the field of immunotherapy was at "the beginning of the end" or "the end of the beginning."¹ In retrospect, I would say it was at the "beginning of the beginning." Have we made progress since then? Finn, in her review of tumor immunology in this issue of the Journal (pages 2704–2715), answers emphatically in the affirmative, and the report by Hunder et al., also in this issue (pages 2698–2703), underscores the remarkable potential of the immune system to eradicate cancer, even when . . . [Full Text of this Article]

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Dr. Weiner is director of the Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC.

Related Letters:

Cancer Immunotherapy
Rosenberg S. A., Dudley M. E., Restifo N. P., Prestwich R., Vile R., Melcher A., Weiner L. M.
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N Engl J Med 2008; 359:1072-1073, Sep 4, 2008. Correspondence

This article has been cited by other articles:

• Rosenberg, S. A., Dudley, M. E., Restifo, N. P., Prestwich, R., Vile, R., Melcher, A., Weiner, L. M. (2008). Cancer immunotherapy.. NEJM 359: 1072-1072 [Full Text]