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This Journal feature begins with a case vignette that includes a therapeutic recommendation. A discussion of the clinical problem and the mechanism of benefit of this form of therapy follows. Major clinical studies, the clinical use of this therapy, and potential adverse effects are reviewed. Relevant formal guidelines, if they exist, are presented. The article ends with the authors' clinical recommendations.
A 45-year-old, premenopausal black woman (gravida 3, para 2, with a history of one spontaneous abortion) presents with menorrhagia and dysmenorrhea that has worsened progressively over a period of 10 years. She does not wish to have any more
The Clinical Problem
Strategies and Evidence
Treatment
Adverse Effects
Areas of Uncertainty
Guidelines
Conclusions and Recommendations
Source Information
From the Department of Radiological Sciences, University of California at Irvine, Orange (S.C.G.); and the Department of Radiology, Georgetown University Medical Center, Washington, DC (J.B.S.).
Address reprint requests to Dr. Goodwin at the Department of Radiological Sciences, University of California at Irvine, 101 The City Dr. S., Rte. 140, Orange, CA 92868, or at sgoodwin@uci.edu.
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Uterine Fibroid Embolization
Walsh C. A., Halpern M., Jesmajian S., Rubin M., Goodwin S. C., Spies J. B.
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N Engl J Med 2009;
361:2292-2294, Dec 3, 2009.
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